Recent Norway Rats Studies Using Warfarin

Health Promotion at Local Level in Norway – Who, What, When, and How: A Response to Recent Commentaries

Strain differences in cytochrome P450 mRNA and protein expression, and enzymatic activity among Sprague Dawley, Wistar, Brown Norway and Dark Agouti rats

Rat cytochrome P450 (CYP) exhibits inter-strain differences, but their analysis has been scattered across studies under different conditions. To identify these strain differences in CYP more comprehensively, mRNA expression, protein expression and metabolic activity among Wistar (WI), Sprague Dawley (SD), Dark Agouti (DA) and Brown Norway (BN) rats were compared. The mRNA level and enzymatic ac...

Challenges of Anticoagulant Rodenticides: Resistance and Ecotoxicology

Control of rodent pests worldwide relies heavily on the use of rodenticides. In the 40s’, O’Connor (1948) isolated and first suggested the use of dicoumarol (a naturally occurring substance responsible for the “sweet clover disease” in cattle) as a rodenticide. In the early 50s’, anticoagulant rodenticides (warfarin and later indane-dione derivatives) replaced the acute poisons with great succe...

بررسی تأثیر تجویز همزمان ویتامین C و وارفارین بر مسیرهای انعقادی خون

Introduction: The aim of the present study was to assess variations in coagulating pathways after simultaneous administration of warfarin and vitamin C. Methods: A total of 50 Wistar rats were selected. The rats were divided into 5 groups (1 group as control and 4 groups as experiment with 10 rats in each group). One group was control group, second group was given only warfarin for 10 days whi...

Norway rat, Rattus norvegicus in metropolitans, a bio-indicator for heavy metal pollution (Case study: Tehran, Iran)

The present research aims to assess the potential use of the Norway rat, Rattusnorvegicus as a bio-indicator for lead and cadmium accumulation in 10 urban zones in Tehran, the metropolitan city, Iran. During April to May 2014 we collected twenty adult Norway rats from the different predefined zones. By referring to the air pollution data collected over 15 years, the sampling areas were detected...